I guess your diffeomorphism is a biholomorphism, or at least an holomorphic map, otherwise there is no hope to say much about it.

Then the best way to look at these things is using differential forms.
Indeed, $\imath \partial \bar{\partial} u =\imath \sum_{i,j}  \frac{\partial^2 u}{\partial z_i \partial \bar z_j} dz_i \wedge d\bar z_j$. 
As is well known, as $\varphi$ is holomorphic (not necessarily bijective), $\varphi^* $ commutes with $\partial$ and $\bar \partial$. 
Therefore $\imath \partial \bar{\partial} u' = \varphi^* \imath \partial \bar{\partial} u$, which you can translate in terms of matrices then, if you want to.