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Hailong Dao
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For a simple, really concrete example you can also look at:

$A=k[X,Y,U,V]/(XY+UX^2+VY^2)$, $X =Spec(A)$, $I=(X,Y)$, $U = D(I)$.

Then the functions $f=-V/X=(Y+UX)/Y^2$ and $g=-U/Y=(X+VY)/X^2$ are defined on $U$. But $Yf+Xg=1$, so $U$ is affine!

Cheers,

Hailong Dao
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