It is possible to make sense of $T^{1/2}$ without some of the particulars mentioned, when $T$ is a positive self-adjoint (densely-defined) operator on a Hilbert space. Namely, Friedrichs' argument (as in Riesz-Nagy, for example) shows that the resolvent $(T-\lambda)^{-1}$ exists and is a bounded operator for $\lambda$ not positive real. In particular, $T^{-1}$ is a bounded operator. It is also positive, so by standard (bounded-operator) spectral calculus admits a positive square root, whose inverse is the desired $T^{1/2}$.
paul garrett
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