Suppose $M = K\backslash G/\Gamma$ is a quotient of a symmetric space by a lattice. I don't know all of the proper adjectives to apply here (e.g. what should be said about $G$ and so on), but I wouldn't be upset if we just took $G=\operatorname{O}(1,n)$ and $K = \operatorname{O}(n)$ so that $M$ is a finite volume hyperbolic orbifold.
Now suppose that $M' \subset M$ is an orbifold locus. I believe it follows that $M'$ is also a lattice quotient (of smaller dimension), and feel free to correct me if I'm wrong about that. Now what can be said about the relationship between the arithmeticity of $M$ and $M'$? E.g. does the (non)arithmeticity of one imply the (non)arithmeticity of the other?