There is a isoperimetric inequality (conjectured by Sikorav and proven by Zuk [Topology 39 (2000) 947--956
]) which holds in every Cayley graph of a group (with modest assumptions, such as countability of the group and finiteness of the generating set $S$), namely: 
$$
|A| \leq diam(A) |\partial A|
$$
Here $\partial A$ is the boundary of the set $A$ (the vertices which are adjacent to an element of $A$ but are not in $A$).

Erschler [Geometriae Dedicata 100: 157--171, 2003] proved that there are even groups where a stronger inequality holds:
$$
|A| \leq K \; diam(A)^k |\partial A|
$$
where $K>0$  and $k \in ]0,1[$.

My question regards a different strenghtening of this inequality:
given a [Cayley graph of a] group and a set $A$ whose complement has no finite connected components, are there $K,k >0$ so that 
$$
(?) \qquad |A| \leq K \; inrad(A)^k |\partial A| ?
$$
where $inrad$ denotes the inradius, i.e. $inrad(A) = max \lbrace r \in \mathbb{N} \mid \exists a \in A$ so that $ B_r(a) \subset A \rbrace$ ; $B_r(a)$ being the ball of radius $r$ around $a$.

**Remarks:**
- $(?)$ holds for any non-amenable group, since, for such groups there is a $K$ so that $|A| \leq K |\partial A|$.

- $(?)$ holds for any group of polynomial growth (choose $K$ and $k$ so that $|B_{r+1}(a)| \leq Kr^k$ then $A$ may be covered by balls of radius $inrad(A)+1$ centered on the vertices of $\partial A$.

- The restricition that the complement of $A$ has no finite connected components might not be necessary. As far as I know $k=1$ might also always work.

- If the inequality $(?)$ for two groups, the it holds for their wreath product. In particular, the inequality holds in the lamplighter group (with $k=1$).

- As far as I could check, the methods of Zuk and Erschler do not seem to yield this inequality.