There are number theorists who understand this subject much better than I do. However, I feel obliged to post an incomplete answer quickly before people have a chance to close this question. ---- There are a lot more connections known between $\pi$ and $e$ and other numbers than between $\gamma$ and other numbers. $\gamma$ may be thought of as a renormalized version of $\zeta(1)$, where $\zeta$ is the Riemann zeta function $\zeta(s) = \sum_{n=1}^\infty n^{-s}$. $$\gamma = \lim_{s\to 1} \bigg(\zeta(s) - \frac{1}{s-1} \bigg)$$ At even integers, $\zeta(s)$ may be rewritten as a sum over nonzero integers, not just the positive integers. That's one explanation for why it is easier to get a handle on $\zeta(s)$ at even values (where it is a rational times $\pi^s$) than at positive odd integer values. See the answers to ["Establishing zeta(3) as a definite integral and its computation."][1] There is some hope. Apéry proved that $\zeta(3)$ is irrational. There are expressions for $e$, $\pi$, $\log 2$, $\zeta(3)$ as periods, definite integrals of elementary functions on $[0,1]$. These can be used in a unified way to prove all of these are irrational (although it's still tricky for $\zeta(3)$), and there are conjectures about the possible rational or algebraic relations between periods. However, so far, no other values of $\zeta$ at positive odd integers are individually known to be irrational. [1]: http://mathoverflow.net/questions/30659/establishing-zeta3-as-a-definite-integral-and-its-computation