Very recently, Hao Huang proved the Sensitivity Conjecture, which had been open for 30 years or so. Here is Huang's preprint, a discussion on Scott Aaronson's blog, and a one-page streamlined proof by Don Knuth.
Huang's proof relies on the existence of an edge weighing $w$ on the hypercube graph $Q_n$. Where if one forms the $2^n\times2^n$ matrix $U_n$ ($= A_n/\sqrt n$ from Huang's paper) where the $(i,j)$-th entry of $U_n$ is $w(v_i,v_j)$ for some enumeration $v_1,\ldots,v_{2^n}$ of the vertices of $Q_n$, then $U_n$ is both unitary and Hermitian. (Huang's matrix is actually symmetric but the more general Hermitian case also covers the Klee-Minty matrix described by Knuth in a footnote.)
It's easy to see that Huang's result holds for any graph $G=(V,E)$ with a weighting $w$ as described above:
Theorem. Suppose there is a weighting $w$ of the edges of the graph $G$ such that the matrix $U$ is both Hermitian and unitary, where the $(i,j)$-th entry of $U$ is $w(v_i,v_j)$ for some enumeration $v_1,v_2,\ldots,v_n$ of $V_G$. Then for every set $H \subseteq V$ with $|H| > n/2$, there is a $v \in H$ which is connected to at least $1/\Vert U\Vert_{\infty}$ vertices inside $H$, where $\|U\|_\infty$ is the maximum absolute value $|w(u,v)|$ ranging over edges $uv$ of $G$.
(In the case of Huang's proof, $U = \frac{1}{\sqrt{n}}A_n$ has all entries in $\{0,\pm1/\sqrt{n}\}$ and the result follows immediately. In the Klee-Minty case the entries of $U = \frac{i}{\sqrt n}\widehat{A}_n$ are all in $\{0,\pm i/\sqrt{n}\},$ using notation from Knuth.)
It is surprising that this was not noticed for 30 years until Huang put the pieces together. (The Klee-Minty cube has been around since 1973!) Why this was never noticed is interesting but, even after this fact, there are still some follow-up questions:
Which graphs have Hermitian unitary edge weights as above?
Is there an algorithm to build such edge weights, given that one exists?
How hard is it to compute the minimum value of $\Vert U \Vert_\infty,$ given that such a weighting exists?
And probably many more related questions... Since there is strong evidence that connections between existing literature are missing, this is an opportune time to fix these lacunas.