A homogeneous space $(X,\tau)$ is a topological space such that for all $x,y\in X$ there is a homeomorphism $\varphi:X\to X$ such that $\varphi(x)=y$. As a previous question implies, the union of an ascending chain of homogeneous spaces need not be homogeneous (example, see below).
What is an example of a Hausdorff space $(X,\tau)$ that does not contain a homogeneous subspace that is maximal with respect to $\subseteq$?
Note. The supremum (union) of an ascending chain of homogeneous spaces need not be homogeneous: Endow $\mathbb{N}$ with the discrete topology and consider the disjoint union $X = (\mathbb{N}\times\{0\}) \cup (\mathbb{Q}\times\{1\})$, where $\mathbb{Q}$ carries the Euclidean topology. Since $X$ is countable, it is the the union of an ascending chain of finite sets, all of which carry the discrete topology and are homogeneous, but $X$ is not.