The compact Hausdorff space  $X = \beta\mathbb{N}$ is another example.  Every regular open subset is the closure of a subset of $\mathbb{N}$ and there are only $\frak{c}$ such subsets but $X$ has $2^{\frak{c}}$ points, and for each such point $p$, the set $X \setminus \{p\}$ is an open set.