The easiest example I can think of is the natural incidence correspondence between $\mathbb{P}^3$ and the parameter space of cubic surfaces. This can be used to show that every cubic surface contains a line; from this it follows easily that every smooth cubic surface contains exactly $27$ lines.
Another example is the moduli space of stable maps constructed by Kontsevich; this parametrizes certain maps from curves to (to stick with a simple case) $\mathbb{P}^2$. It can be used to answer the following question: given $3d-1$ points in $\mathbb{P}^2$ in general position, compute the number $N_d$ of rational curves of degree $d$ passing through these points. It turns out that the values $N_d$ satisfy a certain recursive relation which allows you to compute all these numbers starting from the obvious $N_1 = 1$ (through $2$ points passes exactly one line). You can find the formula here; it yields for instance $N_2 = 5$ and $N_3 = 12$.
Yet another example, again more elementary is the following. The Grassmannian $G = \mathop{Gr}(1, \mathbb{P}^3)$ parametrizes lines in $\mathbb{P}^3$. The computation of the cohomology of $G$ allows you to compute the number of lines which are incident to $4$ fixed lines in general position (it turns out this number is $2$).