Such maps are conformal. A theorem of Liouville says that if $n\geq 3$, the only conformal maps (defined in some region in $R^n$) are Mobius. A Mobius map is a composition of inversions in spheres. For example $x\mapsto x/|x^2|$ is the inversion in the unit sphere. Inversions in all spheres generate the Mobius group.
Derivative of a conformal map is a constant times orthogonal. So if you require it to be orthogonal, you obtain only affine maps.
Liouville's theorem does not hold in dimension $2$. Conformal maps in dimension $2$ are complex analytic function whose derivative is not equal to zero. Your condition implies that the complex derivative has constant absolute value, so it is constant, and again you obtain an affine map.
Usually they include orientation-reversing maps to the Mobius group, so conformal maps can be preserving or reversing orientation.