The cuneiform tablet MS 2351 from the 19th century BC contains the 15-digit sexagesimal number 13 22 50 54 59 09 29 58 26 43 17 31 51 06 40, which happens to equal $20^{20}$. I also seem to remember they constructed a table of reciprocals for numbers of the form $125 \cdot 2^n$ for exponents up to $19$.
Franz Lemmermeyer
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