The configuration space $F(S^m, 2)/\mathbb Z_2$ is diffeomorphic to the total space of the $m$-dimensional vector bundle $E=\gamma^\perp$ over $\mathbb RP^m$, where $\gamma\subset \mathbb R^{m+1}$ is the tautological 1-dimensional line bundle and $\gamma^\perp$ is its orthogonal complement.
To define a diffeomorphism $\phi\colon Tot(E)\to F(S^m, 2)/\mathbb Z_2$ let us pick a point $([v], w)\in Tot(E)$ (where $[v]\in\mathbb R P^m$ and $w\in v^\perp$), such that a vector $v\in \mathbb R^{m+1}$ has the unit norm $||v||_2=1$.
Let $\phi \colon ([v],w)\mapsto\bigl(\frac{v+w}{||v+w||_2}, \frac{v-w}{||v-w||_2}\bigr)\in F(S^m, 2)/\mathbb Z_2$. You can easily verify, that $\phi$ is diffeomorphism.
Computation of the total Stiefel-Whitney class is now straighforward. Let $\pi\colon Tot(E)\to \mathbb R P^m$ be the natural projection, then one has the long exact sequence: $$ 0\to \pi^* E\to TTot(E)\to\pi^*T\mathbb RP^m\to 0, $$ hence $$ w(TF(S^m, 2)/\mathbb Z_2)=w(\pi^*E)w(\pi^*T\mathbb RP^m)=\pi^*(1+a)^{-1}\cdot\pi^*(1+a)^{m+1}=(1+\pi^*a)^m,$$ where $a\in H^1(\mathbb RP^m,\mathbb Z_2)$ is the generator.