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Tried to improve the formulation of the question.
Stefan Kohl
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Invertibility of a matrix whose entries are certain binomial coefficients

Let $l$ be a positive integer. Does the matrix $$ M_l \ := \ \left( \binom{l-(2p+1)}{j} \right)_{0\leq p,j \leq[(l-1)/2]} $$ have nonzero determinant?