What the title said. In a slightly more leisurely fashion:-
Let $X$ be a compact, connected subset of $\mathbb{R}^2$ and let $x\in X$. Can $X\smallsetminus\{x}$ be totally disconnected?
Note that the Knaster-Kuratowski fan shows that, in the absence of the compactness hypothesis, the answer can be 'yes'.
To give credit where it's due, this question was inspired by one that I was asked by Barry Simon.