Let X be an affine variety over ℂ. Consider X(ℂ) with the classical topology, and create the topologists loop space ΩX(ℂ) of maps from the circle into X(ℂ). One can also construct the ind-variety X((t)), whose R-points are given by X(R((t))) for any ℂ-algebra R. Take the ℂ-points of this ind-variety, and give them the usual topology. Is the topological space X((t))(ℂ) thus defined homotopy equivalent to ΩX(ℂ)?
Commentary (based on comments): Note that the space X((t)) is not the base change of X to ℂ((t)) but instead is the restriction of scalars. I'll try to come back with more details, an example or a reference in due time, but if someone has one ready to go, let me know.