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Cohomology of a structure sheaf of a normal affine variety

I can't find the reference for the following fact: Let $X$ be an affine variety and let $Y$ be its smooth resolution. $H^0(X,\mathcal{O}_x)=H^0(Y,\mathcal{O}_Y)$ if and only if $X$ is normal.
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Do the cohomology groups of the structure sheaf of a smooth resolution depend on the resolution?

Let $X$ be an affine variety. Let $Y$ be smooth and let the map $f\colon Y\rightarrow X$ be proper birational. We will call $Y$ a smooth resolution of $X$. Do the cohomology groups $H^i(Y,\mathcal{O}...
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