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The setup is similar to this question, but generalizes the size of the Hankel matrix. We'll define $$d(n,k,r):=\det\left(\binom{2i+2j+k+r}{i+j}\right)_{i,j=0}^{kn-1}.$$ Edit: Thanks to Johann ...

It is well known that for $n>0$ $$d(n)=\det\left(\binom{2i+2j+1}{i+j}\right)_{i,j=0}^{n-1}=1.$$ Computer experiments suggest that more generally $$d(n,k)=\det\left(\binom{2i+2j+2k+1}{i+j}\right)_{i,...