Equivariant cohomology of the complement to the arrangment $\bigcup_{i\neq j}\vec x_i = \vec x_j$? $\DeclareMathOperator\SO{SO}\DeclareMathOperator\SU{SU}\DeclareMathOperator\Conf{Conf}$Let $V=\mathbb{R}^d$ be a $d$-dimensional (Euclidean) vector space over real numbers.
Let $G=\SO(V)$ be the compact Lie group of linear orthogonal transformations of $V$.
Let $\Conf_n(V)$ be the space of $n$-tuples
$\{(\vec x_1,\dotsc,\vec x_n), \vec x_i\in V\}$ of pairwise distinct points in $V$ ($\vec x_i \ne \vec x_j$).
I.e. $\Conf_n(V)$ is an open space that is the complement in $V\times V \times \dotsb \times V = \mathbb{R}^{n d}$
of the union of arrangements of codimension $d$: $\bigcup_{i,j} \{\vec x_i = \vec x_j\}$
There is a natural action of $G$ on $\Conf_{n}(V)$ (namely componentwise).
Question 1): Compute the equivariant (co)homology of  $\Conf_{n}(V)$ with respect to this action of $\SO(V)$:
$$H^{\bullet}_{\SO(V)} (\Conf_n(V);\mathbb{R}).$$
Question 2): The same question for the complex situation. I.e. $V = \mathbb{C}^d$ and the group is $G = \SU(V)$,
and we are interested in the description of
$$H^{\bullet}_{\SU(V)} (\Conf_n(V);\mathbb{C}).$$
Note, that in the case $V= \mathbb{C} = \mathbb{R}^2$ the answer is known to coincide with the cohomology of the open moduli spaces of curves with zero genus and $n+1$ marked points.
Unfortunately for the case of $d>2$ the action of $G$ is no longer free and the total answer should be infinite at least for $d>n\geq 2$, but I will be happy with any reasonable description, even if it will be in terms of cohomology of some finitely generated differential graded algebra.
 A: $\DeclareMathOperator\Conf{Conf}\DeclareMathOperator\SO{SO}$Here is a partial answer, which at least illustrates how to attack these problems using the methods of algebraic topology.
As usual, to compute $H^\ast_G(X)=H^\ast(EG\times_G X)$ where $G$ is a compact Lie group acting on a space $X$, we examine the Leray–Serre spectral sequence of the fibration
$$ X\to EG\times_G X\to BG$$
(my favourite reference for this is the book A user's guide to spectral sequences by McCleary). In the case of Question 1), $X=\Conf_n(\mathbb{R}^d)$ and $G=\SO(d)$ for some $n,d\ge 2$. Since $G$ is connected, $\pi_1(BG)$ is trivial. Both $X$ and $BG$ have the homotopy type of $CW$ complexes of finite type. Therefore Proposition 5.6 in McCleary applies and the SS has
$$E_2^{\ast,\ast} = H^\ast(BG;\mathbb{R})\otimes_{\mathbb{R}} H^\ast(X;\mathbb{R})$$
as a bigraded algebra.
Now the cohomology of the classifying spaces is known to be
$$H^\ast(B{\SO(2k);\mathbb{R})}\cong \mathbb{R}[p_1,\dotsc, p_{k-1},\chi],\qquad H^\ast(B{\SO(2k+1)};\mathbb{R})\cong \mathbb{R}[p_1,\dotsc, p_k],$$
where the $p_i\in H^{4i}(B{\SO(d)};\mathbb{R})$ are Pontryagin classes and $\chi\in H^{2k}(B{\SO(2k)};\mathbb{R})$ is an Euler class (see for instance Corollary 1.90 in Félix, Oprea, and Tanré - Algebraic models in geometry). Meanwhile, the cohomology of configuration spaces is also known, you'll find a full description in Chapter V of the book Geometry and topology of configuration spaces by Fadell and Husseini (see also Section 4 of Farber and Grant - Topological complexity of configuration spaces for the short version). The key point is that $H^\ast(\Conf_n(\mathbb{R}^d);\mathbb{R})$ is generated as an algebra by elements in degree $d-1$, and hence the cohomology is concentrated in degrees $i(d-1)$ for $i=0,1,\dotsc, (n-1)$.
The upshot is that the $E_2$ term is rather sparse, and this should allow you to conclude that the spectral sequence collapses in many cases (the differentials being zero for dimensional reasons). For example, if $d$ is odd then ($d$ is not a multiple of $4$ and) we have
$$ H^\ast_{\SO(d)}(\Conf_n(\mathbb{R}^d);\mathbb{R})\cong H^\ast(B{\SO(d)};\mathbb{R})\otimes_{\mathbb{R}} H^\ast(\Conf_n(\mathbb{R}^d);\mathbb{R})
$$
as algebras graded vector spaces (some extra information may be needed to conclude an isomorphism of graded algebras, see McCleary examples 1.J and 1.K).
A: $\DeclareMathOperator\U{U}$When $V$ is a complex vector space, I computed the equivariant homology of the configuration space in a paper called Operads of moduli spaces of points in $\mathbb{C}^d$,
not with respect to $\U(V)$, but its restriction to $\U(1)$, along the diagonal embedding.  I'm not sure, but I think that extending to $\U(V)$ just tensors this result with $H_*(B{\U(\dim(V)-1)})$, since the answer that I got for $\U(1)$ doesn't seem to allow much room for nonzero operations coming from $H_*(\U(\dim(V)-1))$.
The methods are closely related to those that Mark Grant sketches above, but are nicely packaged using the language of operads.  If you're only interested in rational computations, I think a similar answer is obtainable in the real setting.
