For a short exact sequence of groups $1\rightarrow A\rightarrow B\rightarrow C\rightarrow 1$ there is an associated fibration $K(A,1)\rightarrow K(B,1)\rightarrow K(C,1)$, which can be constructed by realizing the homomorphism $B\rightarrow C$ by a map $K(B,1)\rightarrow K(C,1)$ and the convert it into a fibration. The fiber is $K(A,1)$ (from the associated long exact sequence of homotopy groups).
For a fibration $F\rightarrow X\rightarrow B$, the differential $d_n\colon E_{n,0}^n\to E_{0,n-1}^n$ in the Serre spectral sequence was shown to be equal to the transgression in Hatcher's book on Spectral Sequences (Proposition 1.13). The transgression was defined using (relative) homology groups.
My questions is: From the short exact sequence of groups $1\rightarrow A\rightarrow B\rightarrow C\rightarrow 1$, is there any method to directly compute the transgression of the associated fibration $K(A,1)\rightarrow K(B,1)\rightarrow K(C,1)$, at least for the case $n=2$, without constructing $K(G,1)$'s and considering their homologies?