To help searching: ω(|*G*|) = |π(*G*)|, and I see the latter usually.

A finite simple group *G* with |π(*G*)| = 1 must be cyclic of order *p*. By Burnside's *p*^{a}*q*^{b} theorem, if |π(*G*)|=2, then *G* is not simple.

The finite simple groups with |π(*G*)| = 3 were handled in several specific cases are handled by Brauer, Herzog, Klinger, Leon, Mason, Thompson, and Wales. In particular, it is now known any such group is one of the eight groups listed by Leon–Wales (1974), but this was not known as late as 1976. An important technique is to consider the list of minimal simple non-abelian groups as classified by Thompson in his N-groups papers. This narrowed the problem down to {2,3,*p*}-groups, and indeed *p* had only a few possibilities. Brauer, Leon, and Wales applied character theoretic techniques to classify such groups, and Klinger, Mason, and Thompson used local group-theoretic methods.

The finite simple groups with |π(*G*)| = 4 may have been classified by Cao. With the benefit of the classification, one has explicit order formulas for each finite simple group. Unfortunately, the prime factorizations of these formulas can be very difficult to understand. From the review of Bugeaud–Cao–Mignotte (2001), it appears that we probably have the complete list of groups, but that we may not have the proof of this in my lifetime (just due to silly things like Fermat and Mersenne primes).

In particular, I believe that it is not yet proven that there are only finitely many groups with |π(*G*)| = 4.

I would guess that effectively the answer to your 2nd question then is:

**No** there is no such sequence, but we cannot yet prove this due to number theory problems.

**Edit**: Just to be fickle, let me mention another open problem in that intersection of finite simple groups and number theory. Solomon (2001) attributes this to Peter Neumann:

Are there infinitely many primes *p* such that |PSL(2, *p*)| is a product of six primes? (probably?)

My goodness there are a lot of them! 4721 up to |G| ≤ 10^{20}. Two of the primes have to be 2, one has to be 3, but the other three are sort of like "triplet primes", since they need to divide *p*−1, *p*, and *p*+1. The analogy is a little loose, since we divide (*p*−1)(*p*+1) by 24. The twin prime conjecture is still open, and Solomon describes these problems as "difficult and irrelevant obstacles" for understanding finite simple groups.

I include a selection of papers. I think you get a flavor for the results from these, but there are several I left out, just because the list was getting long.

Brauer, Richard.
On simple groups of order 5⋅3^{a}⋅2^{b}.
Bull. Amer. Math. Soc. 74 (1968) 900–903.
MR236255
DOI:10.1090/S0002-9904-1968-12073-7

Herzog, Marcel.
On finite simple groups of order divisible by three primes only.
J. Algebra 10 (1968) 383–388.
MR233881
DOI:10.1016/0021-8693(68)90088-4
_{(See also:
MR235037
MR249513
)}

Thompson, John G.
Nonsolvable finite groups all of whose local subgroups are solvable.
Bull. Amer. Math. Soc. 74 (1968) 383–437.
MR230809
DOI:http://dx.doi.org/10.1090/S0002-9904-1968-11953-6

Leon, Jeffrey S.; Wales, David B.
Simple groups of order 2^{a}3^{b}*p*^{c} with cyclic Sylow *p*-groups.
J. Algebra 29 (1974), 246–254.
MR338153
DOI:10.1016/0021-8693(74)90098-2
_{(See also:
MR265452
MR268270
MR281792
MR286882
MR308254
MR335623
)}

Klinger, Kenneth.
Finite groups of order 2^{a}3^{b}13^{c}.
J. Algebra 41 (1976), no. 2, 303–326.
MR414689
DOI:10.1016/0021-8693(76)90185-X

Mason, Geoffrey.
A characterization of SL(3, 3). I.
J. Algebra 38 (1976), no. 1, 45–74.
MR407129
DOI:10.1016/0021-8693(76)90243-X

Cao, Zhen Fu.
The simple groups of order 2^{α1}3^{α2}5^{α3}7^{α4}p^{α5}.
Chinese Ann. Math. Ser. A 16 (1995), no. 2, 244–250.
MR1341938

Solomon, Ronald.
A brief history of the classification of the finite simple groups.
Bull. Amer. Math. Soc. (N.S.) 38 (2001), no. 3, 315–352.
MR1824893
DOI:10.1090/S0273-0979-01-00909-0

Bugeaud, Yann; Cao, Zhenfu; Mignotte, Maurice.
On simple K_{4}-groups.
J. Algebra 241 (2001), no. 2, 658–668.
MR1843317
DOI:10.1006/jabr.2000.8742

Zhang, Liangcai; Chen, Guiyun; Chen, Shunmin; Liu, Xuefeng.
Notes on finite simple groups whose orders have three or four prime divisors.
J. Algebra Appl. 8 (2009), no. 3, 389–399.
MR2535997
DOI:10.1142/S0219498809003382