Let $G$ be a reductive group. If one can associate to $G$ a Shimura datum $(G,X)$, then the étale cohomology of the associated Shimura variety $\operatorname{Sh}(G,X)$ is a strong tool for the Langlands correspondence because it carries an action of $G(\mathbb{A})\times\operatorname{Gal}(\mathbb{Q}^{\operatorname{al}},\mathbb{Q})$.
(It is of course more complicated, one should first show that these Shimura varieties admit a model over a number field but this known in general using the theory of special points.)
I have recently heard that some group don't admit a Shimura datum, so my questions are
0- Is this really true? What is the list of known groups which don't have a Shimura datum (any reference)?
1- Is there a criterion to know if $G$ admits a Shimura datum?
2- Is there a criterion to know if $G$ doesn't admit a Shimura datum?
3- If $G$ doesn't have any Shimura datum, then with what to replace Shimura variety? Can Flag varieties be helpful for example?