Let $L \subset \mathbb{C}^n$ be a hyperplane and let $i:L \to \mathbb{C}^n$ be the inclusion. Since $i$ is proper, we have induced maps $i^*: H^k_c(\mathbb{C}^n) \to H^k_c(L)$, and these maps are zero for all $k$ simply because at every degree either one of the compactly supported cohomology groups is zero.
On the other hand, these maps in compactly supported cohomology can be seen to come from a map in the derived category. Indeed, the unit of the adjunction $(i^{-1}, Ri_*)$, together with the fact that $i_* = i_!$, gives a map $$ \alpha: R\Gamma_c \underline{\mathbb{Z}}_{\mathbb{C}^n} \to R\Gamma_c Ri_* i^{-1} \underline{\mathbb{Z}}_{\mathbb{C}^n} = R\Gamma_c \underline{\mathbb{Z}}_{L} $$ and the taking $H^k$ gives the homomorphisms from before, i.e. $H^k(\alpha) = i^*$. My question is whether $\alpha = 0$ (seen as a map in the derived category $D^b(\textbf{Ab})$). Of course, this is stronger than what we said so far, which is $H^k(\alpha) = 0$ for all $k$, see this question.
Edit: if instead of $R\Gamma_c$ we take $R\Gamma$ then the map is nonzero (because it induces an isomorphism after taking $H^0$), so this is fundamentally a question about cohomology with compact support.