Let $X$ be a smooth proper algebraic curve over $\mathbb{C}$. Say a complex local system $\mathbb{V}$ on $X$ is motivic if there exists a dense Zariski-open subset $U\subset X$, and a smooth proper morphism $\pi: Y\to U$, so that $\mathbb{V}|_U$ arises as a subquotient of $R^i\pi_*\mathbb{C}$ for some $i\geq 0$. Fix an integer $r\geq 0$.
Is the set of rank $r$ motivic local systems on $X$, with connected geometric monodromy group, finite?
Here the geometric monodromy group is the Zariski closure of the image of the natural monodromy representation $$\pi_1(X,x)\to GL(\mathbb{V}_x).$$
The question arises from this very interesting recent paper of Joshua Lam, who gives a positive answer when $r=2$ and the genus of $X$ is $2$. Ultimately Lam shows that all such local systems are pulled back from Shimura curves, and then uses Takeuchi's results on finiteness of Shimura curves of bounded genus.
Some remarks:
If instead of $\mathbb{C}$-local systems, one considers motivic $\mathbb{Q}$-local systems, finiteness follows from Deligne's results on finiteness of $\mathbb{Z}$-local systems underlying a polarizable VHS. The same argument shows that there are finitely many motivic $K$-local systems, where $K$ ranges over all number fields of degree at most some constant. One can slightly improve this via arithmetic methods; e.g. if one fixes an $\ell$-adic field $L$, there are finitely many motivic local systems valued in number fields contained in $L$, using the results of this paper of mine.
The analogous statement is false for curves over the algebraic closure of a finite field, which carry a huge collection of motivic local systems.
The statement is false for open curves, as witnessed by e.g. the example of $\mathbb{P}^1\setminus\{0,1,\infty\}$ -- any rank $2$ local system on this curve with quasi-unipotent monodromy at infinity is motivic. Probably to formulate the correct analogue of this question for open curves one needs to fix the conjugacy classes of local monodromy at infinity.
It is necessary to restrict to some condition along the lines of connected geometric monodromy group, to rule out tensor products with finite monodromy local systems, etc.