In non-commutative algebraic geometry, the motto so to speak is to replace the study of a scheme $X$ with the study of the category $D_{qcoh}(X)$ of quasi-coherent sheaves and study the properties thereof. My question is what is the correct analogue for the cohomology of quasi-coherent sheaves in that setting?
For a quasi-coherent sheaf $\mathcal{F}$ on $X$, we can write $$H^n(X,\mathcal{F})\cong \text{Ext}^n(\mathcal{O}_X,\mathcal{F})$$ which would suggest that quasi-coherent sheaf cohomology of a category $\mathcal{C}$ of an object $\mathcal{F}\in \text{Ob}(\mathcal{C})$, we have $$H^\bullet(\mathcal{C},\mathcal{F}):= \text{Hom}_{\mathcal{C}}(G,\mathcal{F})$$ for the "correct" analogue of $\mathcal{O}_X$. The problem is, I don't know what the correct analogue is....
Any pointers?