I am not very familiar with free metabelian groups, so I apologise in advance if this is trivial.
A group $G$ is said to be complete if every automorphism of $G$ is inner. In this case, $\operatorname{Aut}(G) \cong G$ (for centreless groups, this is an equivalent property to being complete). The following classes of groups are known to have complete automorphism groups: f.g. non-abelian free groups [1], f.g. free nilpotent groups of rank $\neq 1,3$ and class $2$ [2], f.g. non-abelian free solvable groups [3].
Hence we have e.g. $\operatorname{Aut}(\operatorname{Aut}(F_2)) \cong \operatorname{Aut}(F_2)$, where $F_2$ is the free group of rank $2$.
Is it known whether every f.g. non-abelian free metabelian group has complete automorphism group?
Note that Bachmuth [4] showed that the automorphism group of a free metabelian group of rank $>2$ is not metabelian (or solvable), and seemed to indicate that the structure for rank $2$ is somewhat tractable. I am curious if anything further has been shown later.
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References
[1] Dyer, Joan L.; Formanek, Edward, Complete automorphism groups, Bull. Am. Math. Soc. 81, 435-437 (1975). ZBL0304.20030.
[2] Dyer, Joan L.; Formanek, Edward, Automorphism sequences of free nilpotent groups of class two, Math. Proc. Camb. Philos. Soc. 79, 271-279 (1976). ZBL0324.20043.
[3] Dyer, Joan L.; Formanek, Edward, Characteristic subgroups and complete automorphism groups, Am. J. Math. 99, 713-753 (1977). ZBL0367.20041.
[4] Bachmuth, S., Automorphisms of free metabelian groups, Trans. Am. Math. Soc. 118, 93-104 (1965). ZBL0131.02101.