It is well known that topological manifolds of dimension $\leq 3$ admit a unique smooth structure. In particular, homeomorphic open subsets of $\mathbb{R}^n$ are diffeomorphic for $n \leq 3$.
So my question is: given a homeomorphism $h:U \rightarrow V$ with $U, V \subset \mathbb{R}^n$, $n \leq 3$ open, is there a natural way to "smooth" it out to get a diffeomorphism?