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Let $A$ be a unital C*-algebra. Let $x,y\in A$ be self adjoint elements in $A$, with $x$ being invertible. Can we say that the spectrum of $x^{-1}y$ is a subset of the real line? I know this is true if $x$ was also positive.

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The golden rule for conjectures in operator theory:

Every ad-hoc conjecture is most likely false for $2 \times 2$-matrices. :-)

So here's a $2 \times 2$-counterexample for the question: Let $A = \mathbb{C}^{2 \times 2}$ and $$ x = \begin{pmatrix} 0 & 1 \\ 1 & 0 \end{pmatrix} \quad \text{and} \quad y = \begin{pmatrix} 4 & 3 \\ 3 & -2 \end{pmatrix} $$.

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    $\begingroup$ Anyway, this question does not really seem to be research level - but I couldn't resist to advertise the "golden rule". :-) (So I marked the answer as community wiki.) $\endgroup$ May 20, 2021 at 15:33

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