This question is related to my post Interpretation of some maps involving cohomology groups.
$C$ is a smooth geometrically integral affine curve over a number field $k$, and $C_1$ is its smooth completion. We focus on the case where $C_1$ differs from $C$ by a point (e.g., $C$ can be an elliptic curve). Denote the absolute Galois group of $k$ by $\Gamma_k$.
By a comment by @abx, we obtain an exact sequence $$1 \rightarrow \bar{k}^* \rightarrow \bar{k}[C]^* \rightarrow \mathbb{Z} \rightarrow 0.$$
We have only one copy of $\mathbb{Z}$ since only one point is missing on $C$.
The long cohomology sequence associated to this exact sequence gives us $$H^1(k,\mathbb{Z}) \rightarrow \mathrm{Br}(k) \rightarrow H^2(k,\bar{k}[C]^*) \rightarrow H^2(k, \mathbb{Z}).$$
In this case the second map is injective. To see why, recall that the cohomology of $\mathbb{Z}$ arises from the exact sequence $$0 \rightarrow \mathbb{Z} \rightarrow \mathbb{Q} \rightarrow \mathbb{Q}/\mathbb{Z} \rightarrow 1$$ which has trivial $\Gamma_k$-action. Therefore $H^1(k,\mathbb{Z}) = \mathrm{Hom}(\Gamma_k,\mathbb{Z})$. This group is trivial since $\mathbb{Z}$ is torsion-free and thus for each finite extension $L$ of $k$ contained in $\bar{k}$, the group $\mathrm{Hom}(\mathrm{Gal}(L/k),\mathbb{Z})$ is zero.
To interpret the elements in $H^2(k,\mathbb{Z})$, we use the fact that $\mathbb{Z}$ has trivial Galois action and so any class of 2-cocycle $f \in H^2(k,\mathbb{Z})$ is of the form $\Gamma_k \times \Gamma_k \rightarrow \mathbb{Z}$ satisfying
$$f(g,hk)+f(h,k) = f(gh,k)+f(g,h).$$
This doesn't seem very helpful in understanding the group, unlike the 1-cocycle case above. However, there are some well-known cases. For example, if $K$ is a local field and $L/K$ is a finite unramified extension with Galois group $G$, or when $G$ is the profinite completion of $\mathbb{Z}$, then $$H^2(G,\mathbb{Z}) = H^1(G,\mathbb{Q}/\mathbb{Z}) = \mathbb{Q}/\mathbb{Z}.$$
Question 1. Is this also true when $G = \Gamma_k$, i.e., is $H^2(k,\mathbb{Z})=\mathbb{Q}/\mathbb{Z}$?
Question 2. For the general case where $C_1\backslash C$ consists of $n$ points, do we still have $H^1(k,\mathbb{Z}^n) = 0$?