The Hirzebruch Riemann-Roch Theorem (HRR) expresses an analytic/algebraic invariant, namely the Euler-Poincaré characteristic of a vector bundle $V$ over a compact complex/algebraic manifold $X$, as the evaluation of a cohomological expression. It has different manifestations in the analytic and algebraic categories; the general form in the analytic category is something like $$ \chi(X,V) = T(X,V), $$ where $X$ is a compact complex manifold, $V$ a holomorphic vector bundle, $\chi(M,V)$ $=$ $\sum_{i \ge 0} (-1)^i\dim_{\mathbb{C}}H^i(X,\mathcal{O}(V))$ the holomorphic Euler-Poincaré characteristic, and $T(X,V)$ a particular cohomological expression (see [1], § 21; [2]).
Subsequently, there were two important generalizations of this result:
The Grothendieck Rieman-Roch Theorem (GRR). This shifts the focus from objects $(X,V)$ to morphisms $f:X \rightarrow Y$, and to coherent sheaves, which are amenable to being pushed forward, and so its algebraic manifestion appears as a commutative diagram $\require{AMScd}$ \begin{CD}\tag{1} K_{\omega}(X) @>f_!>> K_{\omega}(Y)\\ @V\tau_XVV @VV\tau_YV\\ K_{\text{coh}}(X) @>>f_*> K_{\text{coh}}(Y) \end{CD} Here, $f:Y \rightarrow Y$ is a morphism of algebraic varieties, $K_{\omega} :=(K_{\omega}(-),(-)_*)$ an algebraic theory built from coherent sheaves, $K_{\text{coh}} := (K_{\text{coh}}(-), (-)_!)$ a cohomological theory, and $\tau:K_{\omega}\rightarrow K_{\text{coh}}$ a natural transformation of theories (see [3]; [4] Theorem 18.3; [5]; [6]). This generalizes (HRR) insofar as an appropriate instance of (HRR) is obtained from an appropriate instance of (GRR) by applying it to the morphism $X \rightarrow \text{pt}$.
The Atiyah-Singer Index Theorem (ASI). This shifts the focus from objects $(X,V)$ to (pseudo)elliptic operators $D:\mathcal{C}^{\infty}(X,E) \rightarrow \mathcal{C}^{\infty}(X;F)$ on real $\mathcal{C}^{\infty}$-vector bundles over a compact real $\mathcal{C}^{\infty}$-manifold $X$. It takes the form $$ \text{index}(D) = T(X;E,F) $$ where $$ \text{index}(D) := \dim \ker(D) - \dim \text{coker}(D) $$ is an analytical invariant and $T(X;E,F)$ a cohomological (topological) invariant (see [7], Theorem (6.8)). Then (HRR) arises by specializing $D$ to the Dolbeault operator $\overline{\partial}$ (see [8], Theorem (4.3).
Question:
Does there exist a generalization of (ASI) to a relative form, (GAS), say, in a similar fashion as (HRR) generalizes to (GRR), so that we have a square of generalizations
$\require{AMScd}$ \begin{CD}\tag{2} (HRR) @>>> (ASI)\\ @VVV @VVV\\ (GRR) @>>> (GAS) \end{CD}
so that (GAS) specializes, on one hand, to (ASI), and, on the other hand, to (GRR) (and, as the cherry on the cake, do everything equivariantly).
Addendum. Meanwhile, [9] has come to my attention, showing that I am with my question in very good company. Specifically, 6. Further remarks. (3) there refers to loc.cit. Theorem 1 (ASI) and loc.cit. Theorem 3 (HRR) as follows:
In view of Theorem 3 it is natural to hope that the Grothendieck-Riemann-Roch theorem for proper maps of complex manifolds will come out of a suitable generalization of Theorem 1.
Using the notation of loc.cit. one central issue might be, for the special case where the target theory is singular (co)homology, to give, for a proper map $f:X \rightarrow Y$ of real manifolds and an operator $D$ on $X$, an appropriate definition of $\text{ch}(f!D)$.
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[1] Hirzebruch, F. -- Topological Methods in Algebraic Geometry (Reprint of the 1978 Edition). Springer 1978.
[2] O'Brian, N.R. et al. -- Hirzebruch-Riemann-Roch for coherent sheaves, Amer. J. Math. 103, (1981), 253-271.
[3] Borel, A, & Serre, J.-P. -- Le théorème de Riemann-Roch (d'après Grothendieck), Bull. Soc. Math. France 86 (1958), 97 - 136.
[4] Fulton, W. -- Intersection Theory (2nd Ed.), Springer 1998. (Reprint of the 1978 Edition). Springer 1978.
[5] Baum, P. et al. -- Riemann-Roch and topological K-theory for singular varieties, Acta Math. 43 (1979),155-192.
[6] O'Brian, N.R. et al. -- A Grothendieck-Riemann-Roch formula for maps of complex manifolds, Math. Ann. 271, (1985), 493-526.
[7] Atiyah, M.F & Singer, I.M. -- The index of elliptic operators I. Ann. Math. 87 (1968), 484-530.
[8] Atiyah, M.F & Singer, I.M. -- The index of elliptic operators III. Ann. Math. 87 (1968), 546-604.
[9] Atiyah, M.F & Singer, I.M. -- The index of elliptic operators on compact manifolds. Bull. Amer. Math. Soc. 69 (1963), no. 3, 422--433.