Let $\mathbb{D}^2=\{ x \in \mathbb{R}^2 \, | \, |x| \le 1\}$ be the closed unit disk, and set $$\begin{equation*} A(x,y)=\left( \begin{array}{cc} x & -y \\ y & x \end{array} \right) \end{equation*}. $$
Are there smooth maps $A_n: \mathbb{D}^2 \to \mathbb{R}^{4}=M_2(\mathbb{R})$, such that $A_n \to A$ in $L^2(\mathbb{D}^2 , \mathbb{R}^{4})$ and $\det A_n >0$ everywhere on $\mathbb{D}^2$?
Note that it is impossible to approximate $A$ in $W^{1,2}$ by invertible matrices.
Also, a radially symmetric approximation does not exist: Write $A=rR_{\theta}$ in polar coordinates . Then $A_n=f_n(r)R_{\theta}$ is continuous at the origin only if $\lim_{r \to 0}f_n(r)=0$, which implies $A_n(0,0)=0$. So, any non-degenerate continuous approximation must break the radial symmetry of $A$.