It sounds like you want to check out some papers of V. Turchin and W. Willwacher (with collaborators).

For one example, in the paper "Graph-complexes computing the rational homotopy of high dimensional analogues of spaces of long knots", Ann. Inst. Fourier 65 (2015) by Turchin and myself, we describe the complex of deformations of maps from chains on $e_m$ (operad of little disks in dimension $m$) to chains on $e_{m+k}$. The complex is related to the homology of the space of smooth embeddings with compact support of ${\mathbb R}^m$ into ${\mathbb R}^{m+k}$.

The calculation in that paper depends on the relative formality of the little disks operads. The relative formality holds for $k>1$. In the paper
"Relative (non)-formality of the little cubes operad and the algebraic Cerf Lemma" by V. Turchin and T Willwacher they show that relative formality fails for $k=1$, and describe the deformation complex of operad maps $e_m\to e_{m+1}$.