Let $\mathbf{x}_1$ and $\mathbf{x}_2$ be column vectors with entries belonging to the set $\{0,1\}$. In addition, let $\mathbf{A}$ be the adjacency matrix of an arbitrary graph. I want to find vectors $\mathbf{x}=\mathbf{x}_1\otimes\mathbf{x}_2$ with the most number of ones such that
$$\mathbf{x}^{\mathsf{T}}\mathbf{A}\mathbf{x}=0$$
where $\otimes$ denotes the Kronecker product, and $\{.\}^{\mathsf{T}}$ denotes the matrix transpose.