In locale theory, one can produce from any locale $A$ its double negation sublocale $A_{\neg\neg}$ via the nucleus which maps an open $U$ of $A$ to $\neg \neg U$, which is the interior of the closure of $U$. This quotient frame can be viewed as a sublocale of $A$. For many spaces, such as $\mathbb{R}$, the double-negation sublocale $\mathbb{R}_{\neg\neg}$ has no points.
For any locales $A$ and $B$, there is a continuous map, which I believe is mono, $$f : (A \times B)_{\neg\neg} \to A_{\neg\neg} \times B_{\neg\neg}.$$
Does this map have a continuous inverse? That is, are these spaces homeomorphic, and does the double-negation operation commute with products? My hunch is that the answer is no. Taking $A$ and $B$ to both be $\mathbb{R}$, the "diagonal" relation on $\mathbb{R}$ should be clopen in $(\mathbb{R} \times \mathbb{R})_{\neg\neg}$ (in fact, it is equivalent to $\bot$), but I have a feeling that the diagonal of $\mathbb{R}_{\neg\neg} \times \mathbb{R}_{\neg\neg}$ shouldn't be open.
If we have probability distributions $\mu_A : \mathcal{R}(A_{\neg\neg})$ and $\mu_B : \mathcal{R}(B_{\neg\neg})$, then the independent product is $$\mu_A \otimes \mu_B : \mathcal{R}(A_{\neg\neg} \times B_{\neg\neg}).$$
Under what conditions is this independent product the image of some probability distribution over $\mathcal{R}((A \times B)_{\neg\neg})$ of the $f$ defined above? That is, when does this product distribution satisfy the (potentially stronger) regularity properties? I think that this is the case when $A$ and $B$ are both $\mathbb{R}$, because I think that for $\mathbb{R}^n$, a probability distribution $\mu$ on $\mathbb{R}^n$ is absolutely continuous with respect to Lebesgue measure if and only if it can be expressed as a distribution over ${\mathbb{R}^n}_{\neg\neg}$, and since product measures preserve absolute continuity.
I imagine there might be some analogies to be drawn with Dmitri Pavlov's discussion of measurable spaces in this MathOverflow answer.