Consider the family of proper complex genus two curves with affine equation $y^2 = x(x-1)(x-a)(x-b)(x-c)$, defined over an open subset $U$ of $\mathbb{C}^3$. Here, $U$ consists of all triples $(a,b,c)$ such that the corresponding curve is smooth.
Fix a point $x \in U$, and let $C$ denote the corresponding curve. The fundamental group $\pi_1(U,x)$ acts on the set of isotopy classes of simple closed curves on $C$. Is this action transitive on the set of isotopy classes of non-separating simple closed curves? Is this action transitive on the set of isotopy classes of separating simple closed curves? (The answer in both cases is yes if $\pi_1(U,x)$ is replaced by the mapping class group of $C$)