I was surprised to learn that there is (conjecturally) a connection between a cardiac muscle model known as the FitzHugh-Nagumo equations, and untangling knots:
Maucher, Fabian, and Paul Sutcliffe. "Untangling knots via reaction-diffusion dynamics of vortex strings." (arXiv abs (2016).)
If anyone could connect the dots (at a high level) between heart-muscle dynamics, vortices, and knots, I would greatly appreciate it—Thanks!