What are the higher homotopy groups of a K3 suface? All K3 surfaces have the same homotopy type. What are their higher homotopy groups?
I know that $\pi_1$ is trivial, and $\pi_2$ is $\mathbb{Z}^{22}$.
Even if the answer isn't known in all degrees, I'll accept an answer if someone can give me $\pi_3$.
According to this question, you can equivalently tell me the higher homotopy groups of an Enriques surface.
 A: In the paper http://arxiv.org/abs/1303.3328 by Samik Basu and Somnath Basu, it is claimed  (Theorem A) that  the homotopy groups of a simply connected closed 4-manifold $M$ are determined by the second Betti number $k$. In particular, if $k \geq 1$ and $j \geq 3$,
$\pi_j (M) = \pi_j (\#^{k-1} S^2 \times S^3)$.  
For example, using what we know about homotopy groups of spheres, they prove (Corollary 4.10) that if the second Betti number of $M$ is $k+1$ (sorry for the shift from $k$ to $k+1$, I keep the notations of the paper) then 
$\pi_3(M) = \mathbb{Z}^{k(k+3)/2}$
$\pi_4(M)=\mathbb{Z}^{(k-1)(k+1)(k+3)/3} \oplus (\mathbb{Z}_2)^{2k}$
For a K3 surface $M$, $k+1=22$ so
$\pi_3(M) = \mathbb{Z}^{252}$
$\pi_4(M) =\mathbb{Z}^{3520} \oplus (\mathbb{Z}_2)^{42}$
A: Here are some details on how to compute the rank of $\pi_3$. A K3 surface $X$ is, in addition to being simply connected, a compact Kähler manifold, and such spaces are known to be formal in the sense of rational homotopy theory; this means that their rational homotopy can be computed by finding a Sullivan minimal model of their rational cohomology rings, and in particular only depends on the rational cohomology ring. (Terzić's paper linked to in Reimundo's answer uses instead that a compact oriented simply connected $4$-manifold is formal.)
Here is, briefly, how this computation works out, at least if I'm not misreading something. The goal is to build a graded rational vector space $V^{\bullet} = \bigoplus_{k \ge 2} V^k$ and a differential $d$ on the exterior algebra $\Lambda^{\bullet}(V)$ such that 


*

*the cohomology of $(\Lambda^{\bullet}(V), d)$ agrees with $H^{\bullet}(X, \mathbb{Q})$,

*$dV$ is contained in $\Lambda^{\ge 2}(V)$.


The machinery of rational homotopy theory, together with the fact that $X$ is formal and has homology of finite type, then guarantees that we have a natural identification
$$\pi_{\bullet}(X) \otimes \mathbb{Q} \cong \text{Hom}_{\mathbb{Q}}(V^{\bullet}, \mathbb{Q}).$$
In particular, $\dim \pi_{\bullet}(X) \otimes \mathbb{Q} = \dim V^{\bullet}$. So to compute $\dim \pi_3(X) \otimes \mathbb{Q}$ it suffices to figure out how many elements we need in $V^3$.
We already know that we need $\dim V^2 = b_2$, where $b_2 = \dim H^2(X, \mathbb{Q}) = 22$. The cup product $H^2(X, \mathbb{Q}) \times H^2(X, \mathbb{Q}) \to H^4(X, \mathbb{Q})$ takes the form
$$\alpha \cup \beta = Q(\alpha, \beta) \gamma$$
where $Q(\alpha, \beta)$ is the intersection form and $\gamma$ is a generator of $H^4(X, \mathbb{Q})$. The only way to impose these relations on the cohomology of $(\Lambda^{\bullet}(V), d)$ is to introduce elements in $V^3$ whose differentials will impose those relations. Explicitly, let $e_1, e_2, \dots e_{22}$ be an orthogonal basis for $H^2(X, \mathbb{Q})$ with respect to the intersection form, so that $Q(e_i, e_j)$ is some nonzero multiple of $\delta_{ij}$. For $i \neq j$ we need to introduce $\frac{b_2(b_2 - 1)}{2} = 231$ new elements of $V^3$, call them $f_{ij}, i \neq j$, so that we can impose the relations
$$d f_{ij} = e_i \cup e_j.$$
For $i = j$ we need to introduce introduce $b_2 - 1 = 21$ new elements of $V^3$, call them $f_i, 1 \le i \le 21$, so that we can impose the relations
$$d f_i = \frac{e_i \cup e_i}{Q(e_i, e_i)} - \frac{e_{i+1} \cup e_{i+1}}{Q(e_{i+1}, e_{i+1})}.$$
(We cannot introduce the generator of $H^4(X, \mathbb{Q})$ into $V^4$ because we cannot impose a relation that is linear in this generator, so instead we impose the relation that all of the $e_i$ square, up to a normalization, to the same thing.) 
Altogether, we get
$$\dim V^3 = {b_2 \choose 2} + (b_2 - 1) = {b_2 + 1 \choose 2} - 1 = 252$$
as expected from the other answers. 
A: Take a look at Example 6 in [1] which computes $rk \,\pi_2 = 22$, $rk\: \pi_3= 252$ and $rk \: \pi_4 = 3520$ simply using the fact that a quartic in $\mathbb{P}^3$ is a K3 surface and that for such quartics is easy to compute the second betti number $b_2$. The main theorem in Terzic's article is about computing the ranks of $\pi_{2,3,4}$ in terms of $b_2$.
[1]Terzić, Svjetlana. On rational homotopy of four-manifolds. Contemporary geometry and related topics, 375–388, World Sci. Publ., River Edge, NJ, 2004. 
