**Many notions of compatibility between a partially ordered set and a topology on its underlying set are analogous to separation axioms and other well known concepts from general topology.**

One can generalize the separation axioms and other notions such as $T_{2}$,complete regularity, and zero-dimensionality to axioms on ordered spaces that basically say that the order is compatible with the topology in some sense. For instance, following this trend, the notion of Stone-duality becomes the notion of Priestley duality. In this answer, I will outline some of the separation axioms and related axioms for ordered topological spaces. One familiar with general topology should be able to see the analogy between these results regarding ordered topological spaces and general topology.

For example, a topological space $X$ with a partial order $\leq$ is said to be order-Hausdorff if whenever $x\not\leq y$, there is an upper set $U$ and an lower set $V$ with $U\cap V=\emptyset$ and where $x\in U^{\circ},y\in V^{\circ}$. One can show that a partially ordered topology is Hausdorff if and only if $\leq$ is closed in $X^{2}$.

In general topology, we usually want more than simply the Hausdorff separation axiom (remember that most interesting topological spaces are completely regular), and the case is not much different for ordered sets. For ordered spaces, we sometimes want our spaces to be more than just Hausdorff.

An ordered topological space $X$ is said to be completely order-regular if

i. whenever $x\not\leq y$, then there is a continuous order preserving map $f:X\rightarrow[0,1]$ with $f(y)<f(x)$, and

ii. if $x\in X$ and $C\subseteq X$ is a closed set with $x\not\in C$, then there is some continuous order preserving map $f:X\rightarrow[0,1]$ and a continuous order reversing map $g:X\rightarrow[0,1]$ with $f(x)=g(x)=1$ and $C\subseteq f^{-1}[\{0\}]\cup g^{-1}[\{0\}]$.

An ordered topological space $X$ is said to satisfy the Priestley separation axiom if whenever $x\not\leq y$, then there is a clopen upper set $C$ with $x\in C,y\not\in C$.
The ordered topological spaces that satisfy the Priestley separation axiom are said to be totally order disconnected. A Priestley space is a compact totally order disconnected space.

An order-compactification of an ordered topological space $X$ is a compact Hausdorff-ordered space $Y$ such that $X$ is a dense ordered-subspace of $Y$. An order-compactification $Y$ of an ordered topological space $X$ is said to be a Priestley order compactification if $Y$ is a Priestley space.

$\mathbf{Theorem}$(Nachbin) An ordered topological space has an
order-compactification if and only if it is completely order regular.

An ordered topological space $X$ is said to be order-zero-dimensional if satisfies the Priestley separation axiom and the set $\{U\setminus V|U,V\,\textrm{are clopen upper sets}\}$ forms a basis for the topology on $X$.

One can generalize the notion of the Stone-Cech compactification to ordered spaces. If $X$ is a completely order regular space, then there is an order compactification denoted by $n(X)$ called the Nachbin compactification where every continuous order preserving mapping $f:X\rightarrow Y$ such that $Y$ is a compact order-Hausdorff space can be extended to a continuous order preserving map $\overline{f}:n(X)\rightarrow Y$.

A completely order regular space $X$ is said to be strongly-order-zero-dimensional if whenever $f:X\rightarrow[0,1]$, then there is some clopen upper set $U$ with
$f^{-1}[\{1\}]\subseteq U$ and $f^{-1}[\{0\}]\subseteq U^{c}$.

$\mathbf{Theorem}$ Let $X$ be a completely-order-regular space. Then
the Nachbin order-compactification $n(X)$ is a Priestley space iff $X$
is strongly order-zero-dimensional.

$\large\textbf{The Specialization Ordering}$ It is often the case that an ordered topological space does not satisfy any strong separation axioms, but one should never say that these ordered sets have an incompatible topology. It therefore seems like the notion of compatibility between a topology and a partial order depends on context. Every topological space $X$ has an inherent preordering $\leq$ called the specialization ordering where $x\leq y$ if and only if $\overline{x}\subseteq\overline{y}$. Said slightly differently, $x\leq y$ if and only if $x\in\overline{y}$. This preordering is a partial ordering if and only if the space $X$ is a $T_{0}$-space. However, a space $X$ is a $T_{1}$-space if and only if $x\leq y\Rightarrow x=y$ for $x,y\in X$. In other words, a space is a $T_{1}$-space if and only if the specialization ordering is trivial. Often, when one studies ordered topological spaces, the topology coincides with the specialization ordering and thus satisfies no interesting separation axioms. Nevertheless, these ordered topological spaces are important. My answer here also gives information on the specialization ordering in the more general context of closure systems and closure operators while discussing the importance and intuition behind spaces that do not satisfy strong separation axioms.

**It is possible to obtain ordered topological spaces that satisfy strong order-separation axioms from topological spaces that are not even $T_{1}$.** Furthermore, one obtains dualities between categories of ordered topological spaces satisfying strong separation axioms and ordered topological spaces that do not satisfy strong separation axioms. One should therefore give an equal level of importance to ordered topological spaces that do not satisfy strong separation axioms to ordered topological spaces that do satisfy strong separation axioms.

In my own personal research, I have developed the following duality between ordered topological spaces satisfying strong separation axioms and those that do not satisfy strong separation axioms.

I define a lower limit space to be a partially ordered space $X$ such that each set $\downarrow x=\{y\in X|y\leq x\}$ is closed and where the sets $\{\downarrow x\cap U|x\in X,U\,\textrm{is an open upper set}\}$ form a basis for the topology on $X$. It is easy to show that every lower limit space is order-zero-dimensional. If one has a lower limit space, then the collection of open upper sets forms a topology on the set. Furthermore, this restriction to this new topology gives us a duality between the category of lower limit spaces and certain topologies called topological LUB-systems. The importance of topological LUB-systems lies in the fact that LUB-systems are essentially partially ordered sets (the partial order on a LUB-system is the specialization ordering) along with a notion of which least upper bounds are important and which least upper bounds are unimportant.

There is also a duality between order-Hausdorff compact spaces and stably compact spaces. Here when we use compactness or local compactness, we shall not assume that the Hausdorff separation axiom. Recall that a topological space $X$ is locally compact if for each $x\in X$ and open set $U$ with $x\in U$ there is an open $V$ and a compact $K$ with $x\in V\subseteq K\subseteq U$. A subset of a topological space is said to be saturated if it is the intersection of open sets. A space is said to be coherent if the intersection of two compact saturated sets is compact. A space is said to be stably compact if it is compact, locally compact, coherent, and sober.

If $(X,\leq,\mathcal{T})$ is a compact order-Hausdorff ordered topological space, then define a new topology $\mathcal{T}^{s}$ where $\mathcal{T}^{s}$ consists of all open upper sets. Then $(X,\mathcal{T}^{s})$ is a stably compact space and $\leq$ is the specialization ordering on $\mathcal{T}^{s}$.
If $(X,\mathcal{T})$ is a topology, then let $\mathcal{T}^{d}$ denote the topology generated by a subbase consisting of the complements of the compact saturated sets. If $(X,\mathcal{T})$ is a topology, then the patch topology $\mathcal{T}^{p}$ is the topology on $X$ generated by the union $\mathcal{T}^{d}\cup\mathcal{T}$. If $(X,\mathcal{T})$ is a stably compact space, then $(X,\mathcal{T}^{p},\leq)$ is a compact order-Hausdorff space where $\leq$ is the specialization ordering in the space $(X,\mathcal{T})$. These two constructions are inverses and they yield an equivalence between the category of stably compact spaces (with perfect maps) and compact order-Hausdorff spaces.

Several of the results and definitions in this answer (especially regarding spaces satisfying higher separation axioms) can be found in papers by Guram Bezhanishvili and Patrick Morandi. The reader should also consult [2] or [3] for information about ordered topological spaces. I am unsure of whether there is an interesting generalization of these concepts from ordered sets to a broader class of structures.

Nachbin, Leopoldo. Topology and Order. Princeton, NJ: Van Nostrand, 1965.

Gierz, Gerhard; Hofmann, Karl Heinrich; Keimel, Klaus; Lawson, Jimmie D.;
Mislove, Michael W.; Scott, Dana S. compendium of continuous lattices.
Springer-Verlag, Berlin-New York, 1980.

Gierz, G., Hofmann, K. H. , Keimel, K.,
Lawson, J. D. , Mislove, M.
Scott, D. S.; Continuous lattices and domains.
Cambridge University Press, Cambridge, 2003.