Fundamental group of an  analytic hypersurface Let $M$ denote a complex manifold of dimension $n$ and let $X\subset M$ denote an analytic hypersurface. Then it is a standard fact from several complex variables that around a given point $p\in X$ there are open subsets $V\subset X, W\subset \mathbb{C}^{n-1}$ and and a finite-sheeted covering $\pi: V\rightarrow W$ branched over an analytic set $A$. Frequently, $W$ is taken to be a polydisc (see, for example, Griffiths & Harris). Now set $V' = V\setminus \pi^{-1}(A)$ and $W' = W\setminus A$. If $V'$ is connected, then $\pi$ induces a genuine (holomorphic) covering $\pi':V'\rightarrow W'$. 
For appropriately chosen basepoints $v_0, w_0$ in $V',W'$, respectively, covering space theory says that $\pi'$ induces an injection $\pi_1(V',v_0)\rightarrow \pi_1(W',w_0)$, and in some cases (e.g. involving curves) this might be enough to figure out $\pi_1(V',v_0)$ if $\pi_1(W',w_0)$ is known. If $V$ were smooth, $\pi^{-1}(A)$ would be an analytic subset of complex codimension 1 and the inclusion $V'\hookrightarrow V$ would induce a surjection $\pi_1(V',v_0)\rightarrow \pi_1(V,v_0)$, determining a presentation for $\pi_1(V,v_0)$. However, $V$ may not be smooth, and I am not sure in what generality this map is still a surjection, although clearly I'd like to know.
What I really want to do is determine a presentation for $\pi_1(X,x_0)$. 
It seems that one way to to go about doing this would be to construct an open cover $(V_{\alpha})$ of $X$ consisting of open sets with the same properties possessed by $V$ above AND such that $(V_{\alpha})$ satisfies the hypotheses of the Seifert-van Kampen Theorem (see, for example, Hatcher). In the very best case, one could arrange for the intersections $V_{\alpha}\cap V_{\beta}$ to be simply-connected and for the triple intersections to be path-connected. Then one could read off a presentation of $\pi_1(X,x_0)$ in terms of the presentations of the $\pi_1(V_{\alpha}, v_{0\alpha})$.   
I'd be interested to know when such a cover $(V_{\alpha})$ exists, especially for $n\geq 3$. 
I am also interested in hearing about any known methods of calculating the fundamental group of an analytic hypersurface (not necessarily smooth), in general or in special cases (for example, the Lefschetz Hyperplane Theorem can be used on certain projective hypersurfaces). 
(Note: I'd like to consult Dimca's book "Singularities and Topology of Hypersurfaces", but I'll be away from my library for the next few weeks.)
 A: It should be said that van Kampen's  paper  "On the connection between the fundamental groups of some
  related spaces". Amer. J. Math. 55 (1933) 261--267, gives a formula for the case of a union of two spaces with non-connected intersection, and this was needed for his work on algebraic curves: "On the Fundamental Group of an Algebraic Curve". Amer. J. Math. 55 (1933), no. 1-4, 255–267. The non-connected case  seems to me best handled in modern terms using groupoids. (See my web pages.) (An earlier version of the theorem in the connected case and for simplicial complexes was given by Seifert.) 
Since homotopy groups are mentioned in the last comment, I mention the higher order theorems of the Seifert-van Kampen type of which the 2-d version was  given in my paper with Philip Higgins , ``On the connection between the second
relative homotopy groups of some related spaces'', Proc.
London Math.  Soc. (3) 36 (1978) 193-212.  This uses extensively the notion of crossed module, and has been applied  to give explicit calculations of homotopy 2-types, and second homotopy groups. (Again, see references on my web pages). 
In view of the provenance of van Kampen's paper, it would be very interesting to know if such higher theorems are applicable to the situation of the question. 
@Kevin Kordek: September 2013: I should add that Grothendieck was interested in these possibilities. See the last problem stated in the set of problems and "Future directions?" given in our new book on "Nonabelian algebraic topology"; more details and pdf's available from here. Part of his comment is as follows: 
"It seems to me, in any case, that this
$\underset{\to}{\lim}$-operation ["higher order van Kampen
theorem"] in the context of homotopy types is of a very fundamental
character, with wide range of theoretical applications. To give just
one example, relying on the existence of such a formalism, it is
possible to give a very simple explicit algebraic description of the
full homotopy types of the Mumford-Deligne compactifications of the
modular topoi for complex curves of given genus $g$, say, with $\nu$
"marked" points, in terms essential1y of such a (finite) direct
limit of $K(\pi, 1)$-spaces, where $\pi$ ranges over certain
"elementary" Teichm\"uller groups (those, roughly, corresponding to
modular dimension $\leq 2$), and to give analogous descriptions,
too, of all those subtopoi of the previous one, deducible from its
canonical "stratification" at infinity by taking unions of strata.
In fact, such descriptions should apply to any kind of ``stratified"
space or topos, as it can be expressed (in an essentially canonical
way, which apparently was never made explicit yet in this
literature) as a (usually finite) direct limit of simpler spaces,
namely the "strata", and "tubes" around strata, and "junctions"
of tubes, etc."
So   I probably missed out on not pursuing this, partly because of pursuing work with J.-L. Loday on even more powerful Higher van Kampen type theorems. 
