The Grommer inequalities are equivalent to RH and formulated on page 20 of Conrey - Riemann's hypothesis:
Let $$\Xi(t) := \xi(1/2+it).$$
Then RH is equivalent to : All zeros of $\Xi(t)$ are real. The functional equation for $\zeta$ is equivalent to $\Xi(t) = \Xi(-t)$. Let $Y(t):= \Xi(\sqrt{t})$ and let
$$-\frac{Y'(t)}{Y(t)} = s_1+s_2t+s_3t^2+\dotsb$$
and set $k(a,b) := s_{a+b}$. Let $K_N := ((k(m,n))_{1\le m,n\le N}$ and $D_N:=\det(K_N)$.
Then the Grommer inequalities are equivalent to RH:
$$\text{RH} \iff D_N > 0 \forall N \in \mathbb{N}.$$
But this is by the Sylvester criterion equivalent to thematrices $K_N$ being positive definite ($K_N>0$) for all $N \in \mathbb{N}$.
What is unclear to me: Is $K_N > 0$ $\forall N \in \mathbb{N}$ equivalent to the function $k$ being positive definite over the natural numbers?
If this is the case, one could have a candidate for the Hilbert–Pólya conjecture: By the Moore–Aronszajn theorem, there exists a mapping:
$$\phi: \mathbb{N} \rightarrow H$$
in some Hilbert space $H=l_2$, such that:
$$k(a,b) = \left\langle \phi(a), \phi(b) \right\rangle \forall a,b \in \mathbb{N}.$$
Define on a dense subspace $D :=\{ x | x \text{ has only finitely many nonzero entries } x_i\} \subset l_2$ the operator $R$ via:
$$R(e_n) := \phi(n)$$
and for $x = \sum_{i=1}^N x_i e_i \in D$:
$$R(x) := \sum_{i=1}^N x_i R(e_i), R: D \rightarrow D$$
where $(e_n)_{n \in \mathbb{N}}$ is an orthonormal basis in the Hilbert space $l_2$.
Set $O:= R^*R$. Then $O:D \rightarrow D$ is a positive, densely defined, self-adjoint operator, with the property:
$$\left\langle O(e_m),e_n \right\rangle = \left\langle R^*R (e_m) , e_n \right\rangle = \left\langle R(e_m),R(e_n)\right\rangle = k(m,n).$$
Then by Grommer inequalities and Sylvester's criterion (/modulo my question above can be answered positively) :
$O$ is a positive operator with the property $O=R^*R$ for some $R$ and $\left\langle O(e_m),e_n \right\rangle = k(m,n).$ $\iff$ $k$ is a positive definite function on the natural numbers $\iff$ RH.
Edit: There seems to be confusion about this question, so please let me clarify: I am not saying that this question is proving RH. What I am saying is, that $O>0 \iff k > 0 \iff \text{Grommer's ineq.} \iff RH$ and so, this makes $O$ an candidate for the Hilbert-Polya conjecture in some wide sense.
Second question: I tried to implement this idea in Sagemath to have some empirical backup, but without success since Sagemath cannot cope with the $\sqrt{t}$ in the series expansion, but it seems that Mathematica can, since I tried a little bit on Wolfram Alpha. Is it possible for someone with Mathematica to try and implement this idea for empirical backup? (I would define the matrix $K_N$ and see if it is positive definite for say $N=1,\dotsc,200$, and look at the eigenvalues of the matrix and compare them with OEIS sequence.)
Related question: Spectrum of "infinite-Gram matrix"?