Let $Y,Z$ be $n\times k$ matrices and assume all columns have been standardized such that their means are zero and variances 1. I seek an $n\times n$ permutation matrix $P$ such that
$$\left\Vert Y^{T}P^{T}Z-\Omega\right\Vert$$
is small, where $\Omega$ is a specified cross-correlation matrix. For intuition, you might consider matching $n$ pairs of individuals up to form couples that are correlated on $k$ traits (represented by $Y$, $Z$) such that a particular cross-couple correlation structure $\Omega$ is induced.
When the above norm $\left\Vert \cdot\right\Vert $ is the Frobenius norm, this is the quadratic assignment problem (QAP):
$$\min_{P\in\mathcal{P}}\ \mathrm{tr\,}YY^{T}P^{T}ZZ^{T}P-2\mathrm{tr\,}P^T Z\Omega Y^T,$$
which seems to be a particularly nasty NP-hard problem. In practice, I don't really care what norm $\left\Vert \cdot\right\Vert $ is: given a finite amount of computation, I'd just as soon get closer to the optimal solution to a similar problem. In my application $n$ is large, so I presume I'll be solving a relaxation of the above (e.g., solve over the space of doubly stochastic matrices). My question is, is there any choice of $\left\Vert \cdot\right\Vert $ for which this problem becomes substantially easier in terms of finding a "good enough" solution?