While considering the zero curvature equation $U_t - V_x + [U, V] = 0$, I developed a similar problem, albeit one that discards time dependence entirely. For a given $U(x)$ and $C(x)$, find $V(x)$ such that $[U, V] - V_x = C(x)$ holds. After considering this question, I believe that the system would either have a single solution or an infinite class of solutions depending on the choice of $C$ and $U$. In the question, I found the method involving the Kronecker product to be more suited for matrix functions as I ultimately hope to prove that the compatibility condition is isospectral. (I do not want to assume that the eigenvalues are constant across space, as I believe that it would produce a circular argument.)
I had also wondered if the system could be transformed by finding $\gamma(x)$ and $\eta(x)$ such that $[U + \gamma, V + \eta] = [U,V] - V_x$. Ultimately, I realized such an attempt would reduce to solving $[\eta, \gamma] + [V, \gamma] + [\eta, U] = V_x$, which is no simpler than the original equation. Most of the difficulty arises from the lack of commutativity of the matrix product.
Question: For a given $U(x)$ and $C(x)$, can one solve for $V(x)$ such that $[U, V] - V_x = C(x)$ holds?