This was an interesting question posed to me by a friend who is very interested in commutative algebra. It also has some nice geometric motivation.
The question is in two parts. The first, as stated in the title, asks whether every Noetherian commutative ring a quotient of a Noetherian Domain? Geometrically, this question asks if every Noetherian affine scheme can be embedded as a closed subscheme of an integral scheme.
The second part of the question is that if the first part is answered in the affirmative, then is every (regular) Noetherian ring a quotient of a regular Noetherian domain? Geometrically, this asks whether every affine Noetherian scheme can be embedded as a closed subscheme of a smooth integral scheme.
We managed to make some progress on the first part of the question. We looked at finite products of Noetherian domains and showed that if the Noetherian domains A and B contain a common Noetherian subring C such that A and B are essentially of finite type over C, then $A \times B$ is a quotient of a Noetherian domain. But we weren't able to remove the essentially finite condition and the simplest example which we were unable to work out was $\mathbb{Q} \times \mathbb{C}$.