Take a smooth complex projective variety $X$, consider $H^k(X,\mathbb Z)$, and take the global period domain as described, for example, in Voisin's Hodge theory book, 10.1.3: it's a subset of a flag variety, modulo the action of $\operatorname{GL}(H^k(X,\mathbb Z))$. We can also take the global period domain for $H^k(X,\mathbb Q)$, which is the same subset modulo $\operatorname{GL}(H^k(X,\mathbb Q))$, which is no longer a discrete group.
When can we expect the map from the period domain for integral Hodge structures to the period domain for rational Hodge structures to be generically injective? What about the same map for polarized Hodge structures on $H^k_\text{prim}$, or the map from the polarized period domain to the unpolarized one? It seems like this should be in a textbook, but I haven't found it.
Some remarks in the introduction to Voisin's paper "Schiffer variations..." suggest that this forgetful map is generically injective for hypersurfaces of most degrees and dimensions, and for curves of genus $g \ge 4$ but not genus 3. I'm not even sure what happens for K3 surfaces.