Marty is definitely correct about the origin of the terminology in the study of homogeneous spaces $G/H$ of reductive Lie groups. Due to the special example involving a quotient of special orthogonal groups the handy term *spherical" got attached to the subgroup $H$ or the homogeneous space. In turn, this was carried over to the situation of algebraic groups and similar quotients in the algebraically closed case, where spherical varieties could be characterized as those homogeneous spaces admitting a dense orbit under a Borel subgroup. For instance, look at the introduction of an influential paper by Brion-Luna-Vust which appeared in Inventiones 84 (1986) with the title Espaces homogènes sphériques. While the label spherical variety is convenient, it loses its literal sense in this generality.