For $X$ a countable $T_{3_{1/2}}$ space then the Stone-Cech compatificationcompactification $\beta(X)$ has size $2^{2^{\aleph_0}}$.
Also Shelah has written things about Dowker spaces of size $\aleph_{\omega+1}$.
Still in topology, $\mathbb{N}^{\aleph_1}$ is not a Cech-complete space. Recall that a Cech-complete space is space where the remainder $\beta(X) \backslash X$ is a $G_\delta$ set.