Have you looked at Bernstein's lectures on D-modules? He proves a result relevant to your questoinquestion in Lec. 3, Sec. 14: for an affine embedding Y --> X with Y irreducible, if E is an OY-coherent DY module (i.e. a vector bundle with a flat connection) then the !* direct image from E can be characterized as the unique irreducible subquotient of either the * or ! direct image which has nonzero restriction to Y. Since it can be easy in such situations to compute the * direct image, this may be a good way to get a handle on the other functors too. For example, I think one can see from this that if we take the embedding of the origin into the affine line, then both the * and !* direct images of OY=k (the ground field) are A(1)/A(1)t, where t is the coordinate on the affine line and A(1)=DX is the 1-dimensional Weyl algebra k[t,d/dt]. This quotient is rightly considered the "delta-function" A(1)-module, since its generator δ satisfies tδ=0. I'm not sure how similar to this case your general situation will be. But certainly by Kashiwara's theorem one knows that the * direct image (and hence the !* direct image) will be supported on the subvariety Y.