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The conjecture statedas written is false:
Let $N=194+(2*3*5*7*11*13)*2n$, $k=N-2$, where $n$ is a natural number.
Then $C(N,k)=C(N,2)=(97+2*3*5*7*11*13*n)(193+2*3*5*7*11*13*2n)$, having no prime factors $\leq 13$.
The conjecture stated is false:
The conjecture as written is false: