My own publications have all been in one tiny specialty in nuclear physics, with only one exception, which was "multidisciplinary" in the sense on touching multiple areas within physics. I found the experience of writing that paper somewhat unnerving, because it was difficult to tell whether what I was doing met the standard for being interesting, original, or even correct. When you're working within your own tidy little area, no matter how small, boring, and inconsequential, it's much easier to judge whether your peers would consider it to be good work.

Arxiv has performed a valuable service for you, and they've done it free of charge and without any ulterior motives. They've told you that this paper has problems, and in my opinion, it does. Others have pointed out that it only has one reference. This is not really the issue per se. Rather, the issue is that your paper doesn't make the case for itself as being important. One of the functions of references is to establish that, for example, people have already posed this problem and worked on it, or that it fills a need that has already been identified.

Regardless of whether your paper has many references or few, it needs to make the case that it is important, original, and of interest to someone in some field. The first step in making that case is simply to assert that. Can you assert that this work is of interest to mathematicians? To epidemiologists? If so, then assert that, possibly as the first sentence of the abstract. Of course, being able to assert this implies being able to back it up with an argument. That argument should be either explicit or implicit in your paper and its references.