Why I do not have a relevant counterexample yet, I decided to write an extended comment on related PoincarePoincaré and Sobolev inequalities. The purpose was to place the question in the right context, provide a source that contains many related references and mention a result (inequality (*)) in the positive direction that is strictly related to the inequality in the question.
A lot is known about PoincarePoincaré inequalities on Cayley graphs of finitely generated groups of polynomial growth.
Denote by $|B|$ volume (number of points) in a of a ball $B$. Denote also by $f_B$ average of $f$ on $B$. Also $|\nabla f(x)|=\sum_{y\sim x}|f(x)-f(y)|$ where $x\sim y$ mean that $x$ and $y$ are connected by an edge.
Theorem. If $G$ is a finitely generated group of polynomial growth i.e. volume of a ball of radius $n$ in the associated Caley graph is $\approx n^d$ for some positive integer $d$. Then for any ball $B$ of radius $n$ the following Sobolev-Poincare inequality is true: $$ \left(\frac{1}{|B|}\sum_{x\in B}|f(x)-f_B|^q\right)^{1/q}\leq C n \left(\frac{1}{|B|}\sum_{x\in B}|\nabla f(x)|^p\right)^{1/p} $$ where $1\leq p<d$ and $1\leq q\leq dp/(d-p)$. The constant $C$ does not depend on $B$.
In particular taking $p=q=1$ yields $$ \sum_{x\in B}|f(x)-f_B|\leq C n \sum_{x\in B}|\nabla f(x)| \qquad\qquad (*) $$
This is similar to your inequality but the difference is that you take the $\ell^1$ norm on the ball and not on the whole graph. Also the graph cannot be arbitrary. You need some structure in order to prove the PoincarePoincaré inequality.
For a proof of the above result and many references see:
P. Hajłasz, P. Koskela, Sobolev met Poincaré. Sobolev met Poincaré. Mem. Amer. Math. Soc. 145 (2000), no. 688.